DONATE
FOR PHYSICIANS
HEALTH AND NUTRITION
ETHICAL RESEARCH & EDUCATION
  Action Alerts
  Education and Training
  Research
  Animal Testing and Alternatives
  Health Care Professionals
  Breaking Research News
MEDIA CENTER
LEGISLATIVE FOCUS
CLINICAL RESEARCH
EDUCATIONAL LITERATURE
MEMBERSHIP
SHOP

Connect with Us

 

 

The Physicians Committee



BREAKING RESEARCH NEWS August 1, 2014

Stem Cells from Patients with Lou Gehrig’s Disease Provide Novel Insights into Disease Mechanisms

August 1, 2014

Stem Cells from patients with Lou Gehrig's Disease provide novel insights into disease mechanisms

According to a new report in Cell Stem Cell, researchers recently discovered new mechanisms behind nerve cell dysfunction in amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease. Using stem cells from ALS patients, researchers discovered how certain genetic mutations interfere with the ability of motor neurons to function normally, an effect never observed in mouse models of ALS. This in vitro model will allow scientists to further study the mechanisms underlying ALS as it occurs in humans.

Kiskinis E, Sandoe J, Williams LA, et al. Pathways disrupted in human ALS motor neurons identified through genetic correction of mutant SOD1. Cell Stem Cell. 2014;14:781-795.
 

Subscribe to the Physicians Committee’s Breaking Research News.

Breaking Research News is a service of the Physicians Committee for Responsible Medicine, 5100 Wisconsin Ave., Ste. 400, Washington, DC 20016, 202-686-2210. Join the Physicians Committee and receive the quarterly magazine, Good Medicine.



 

2014 Archive

This site does not provide medical or legal advice. This Web site is for informational purposes only.
Full Disclaimer | Privacy Policy

The Physicians Committee
5100 Wisconsin Ave., N.W., Ste.400, Washington DC, 20016
Phone: 202-686-2210     Email: pcrm@pcrm.org