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New Lab-on-Chip for Nonanimal Toxicity Testing
Researchers recently developed a new lab-on-chip device that allows for faster testing of the effects of drugs or toxic substances on human components like blood. The chip is able to mimic detoxification reactions that would occur in the human body. In addition, it contains engineered artificial microchannels that have the advantage of quickly mixing the byproducts of tested substances with human products. The chip allows for the very fast reactions in humans to be examined in detail outside of the human body and will help replace the use of animal testing for such purposes.
The full reactor and mixing unit on a chip. Credit: University of Twente
References
- Van den Brink FTG, Wigger T, Ma L, et al. Oxidation and adduct formation of xenobiotics in a microfluidic electrochemical cell with boron doped diamond electrodes and an integrated passive gradient rotation mixer. Lab Chip. 2016;16:3990-4001. doi: 10.1039/C6LC00708B.
