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  1. Ethical Science News

  2. Apr 5, 2017

Stem Cell Model Identifies Eating Disorder Gene

Study in a Sentence: Using skin cells isolated from patients with the eating disorder anorexia nervosa, researchers created a new stem cell model of this condition and identified a novel gene (tachykinin 1 receptor) involved in this disorder.

Healthy for Humans: The novel gene implicated in anorexia nervosa by this study can serve as a new drug target for this disorder. This gene was previously found to play a role in the regulation of the metabolic system by the brain, suggesting a new molecular insight into this disorder.   

Redefining Research: The study provides a new human-based research tool (i.e., stem cell model of anorexia nervosa) for scientist to further investigate other unknown underlying molecular and cellular mechanisms involved in anorexia nervosa.

References

  1. Negraes PD, Cugola FR, Herai RH, et al. Modeling anorexia nervosa: transcriptional insights from human iPSC-derived neurons. Transl Psychiatry. 2017;7:e1060. doi: 10.1038/tp.2017.37.

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