The Physicians Committee Is Accelerating Nonanimal Methods at the 64th Annual Meeting of the Society of Toxicology, March 16-20

The Physicians Committee for Responsible Medicine’s scientists and policy professionals are joining other top researchers, academics, industry leaders, and regulatory experts to advance innovative nonanimal toxicological approaches at the Society of Toxicology’s 2025 Annual Meeting. The team will present cutting-edge, human-specific, nonanimal approaches; build on collaborations; and host events to drive the future of ethical and effective science.
To support talented early career innovators eager to replace animal use, we are providing need-based travel awards. If you are attending SOT, join us in accelerating research that is more predictive, faster, and advances human health without harming animals.
(*All times are in Eastern Standard Time)
Hesperos Technology for Toxicology Research: From Development to Approval
Description: The Physicians Committee for Responsible Medicine, the Johns Hopkins Center for Alternatives to Animal Testing, and Hesperos are partnering to host a free, hands-on workshop to showcase Hesperos technology and applications. Participants will tour the Hesperos facility, hear from scientists working with the models, gain first-hand experience, and hear from leaders working to advance human-specific nonanimal approaches. This event is free and limited to 20 participants, with advance registration required. Transportation and refreshments will be provided.
Ancillary Event
12:15 – 4:45 p.m., Sunday, March 16, 2025
Located offsite at Hesperos, Inc. (Transportation provided to/from SOT for registered attendees)
NURA Program Expands Free Human-Based Toxicological Training
Dr. Eryn Slankster-Schmierer will present on the Physician Committee’s NAM Use for Regulatory Application (NURA) program, which increases the accessibility of NAMs by providing scientists and regulators with free, convenient, and on-demand education in nonanimal methods to help modernize regulatory toxicity assessments.
Poster presentation, #P376
Authors: Eryn Slankster-Schmierer, PhD; Shagun Krishna, PhD; Allison Martin, MSc; and Elizabeth Baker, JD
1:45– 4:15 p.m., Monday, March 17
W Hall A2‚ Orange County Convention Center
ICAPO and ICAPPP Annual Meeting
The Physicians Committee serves as the secretariat of the International Council on Animal Protections within the OECD (ICAPO). SOT provides a rare opportunity to bring many members of this international group together with its sister organization, the International Council on Animal Protection in Pharmaceutical Programs (ICAPPP), to strategize in person international influence.
Hosts: Eryn Slankster-Schmierer, PhD, and Elizabeth Baker, JD
This is a private event on Monday for current ICAPO members.
Contact Eryn Slankster-Schmierer at eslankster [at] pcrm.org (eslankster[at]pcrm[dot]org) for more information.
Multiscale Risk Characterization of Chemical Cardiotoxicity: Integrated In Vitro and In Silico Multiscale Modeling Reveals Cardiovascular Risk From Chemical Exposures
Dr. Shagun Krishna will present on multiscale risk characterization of chemical cardiotoxicity, integrating high-throughput screening (HTS) data, in vitro-to-in vivo extrapolation (IVIVE), physiologically based pharmacokinetic (PBPK) modeling, and geospatial analysis. This study identifies cardiovascular risks from environmental and industrial chemical exposures and highlights the need for nonanimal methods to improve chemical risk assessment and regulatory decision-making.
Presenter: Shagun Krishna, PhD
10:45– 11:00 a.m., Thursday, March 20
Room W205A‚ Orange County Convention Center