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  1. Innovative Science News

  2. Jul 16, 2021

Rapid 3D Bioprinting of Human Tissues for Drug Screening and Tissue Modeling

multiwell plate
Photo: Getty Images

Researchers at University of California San Diego integrated a 3D bioprinting platform with large-scale experimental capabilities to enable the rapid generation of in vitro 3D human tissue models with up to 96 samples per batch.

Study in a Sentence: Researchers at University of California San Diego integrated a 3D bioprinting platform with large-scale experimental capabilities to enable the rapid generation of in vitro 3D human tissue models with up to 96 samples per batch.

Healthy for Humans: Advances in 3D bioprinting allow for human tissue models with complex spatial, mechanical, and physiological properties that are capable of overcoming the reproducibility and translatability issues that limit 2D in vitro systems and the use of animals in disease modeling and preclinical testing. 

Redefining Research: However, there is still a need for high quantity, high speed production of 3D bioprinting for use in biological, chemical, and pharmaceutical research. With their high throughput 3D bioprinter, dubbed HT-3DP, these researchers have accomplished just that, demonstrating proof of principle in a rapid chemotherapy drug screen using 96 replicated samples of bioprinted cancer tissue.

References

Hwang HH, You S, Ma X, et al. High throughput direct 3D bioprinting in multiwell plates. Biofabrication. 2021;13(025007). https://doi.org/10.1088/1758-5090/ab89ca.

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