Human Advanced In Vitro Model Initiative

Proposals will be reviewed based on the following criteria:

1. Novelty

Proposals should present a novel approach, concept, or methodology that advances scientific knowledge or technological innovation. Clearly explain how the project differs from existing solutions and what unique contribution it makes to the field. Highlight any breakthrough potential or innovative aspects of the research.

2. Completeness and Scientific Rigor

Ensure the proposal is well-structured, logically developed, and based on sound scientific principles. Clearly define the research objectives, hypotheses, and methodology.

3. Complementarity to Existing Solutions

Describe how the project fits into the broader scientific landscape and complements existing solutions rather than duplicating them. Identify any gaps in current methodologies or technologies that the research addresses and explain how the approach integrates with or enhances existing knowledge and applications.

4. Feasibility, Chances vs. Risks

Consider the feasibility of the project by assessing the stated objectives, required resources, and potential challenges. Proposals should demonstrate a clear understanding of the balance between potential breakthroughs and associated risks, ensuring a practical and achievable research plan. A risk-benefit analysis is NOT required for this application.

5. Impact on 3Rs (Replacement, Reduction, and Refinement)

Projects should align with the principles of the 3Rs, particularly in the context of replacing animal testing. Proposals must include a well-informed estimate of the number of animals that will be replaced by this project, specifying the species and types of animal tests involved.

6. Relation to InSphero Offers

The HUMAIN initiative funds researchers to utilize InSphero's technology and services. Proposals with study designs that can be achieved with InSphero’s offerings will be given preference.