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Lower Cholesterol May Lower Risk of Dementia
Low-density lipoprotein cholesterol (LDL-C) levels below 70 mg/dL were associated with a 26% lower risk of all-cause dementia and a 28% lower risk of Alzheimer’s-disease-related dementia, according to a new retrospective cohort study including over 100,000 matched pairs.1 LDL-C levels below 30 mg/dL did not have a protective or detrimental effect in this study. Vegan and vegetarian diets have proved to be effective at lowering total and LDL cholesterol levels.2
References
- Lee M, Lee KJ, Kim J, et al. Low-density lipoprotein cholesterol levels and risk of incident dementia: a distributed network analysis using common data models. J Neurol Neurosurg Psychiatry. 2025;0:1-9. doi:10.1136/jnnp-2024-334708
- Koch CA, Kjeldsen EW, Frikke-Schmidt R. Vegetarian or vegan diets and blood lipids: a meta-analysis of randomized trials. Eur Heart J. 2023;44(28):2609-2622. doi:10.1093/eurheartj/ehad211
