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New Paper Suggests Need for Human-Relevant Alzheimer’s Research
A new commentary in the Journal of Alzheimer’s Disease by Physicians Committee medical research specialist Francesca Pistollato, Ph.D., and colleagues, addresses the need to refocus current research efforts on human-based methods, such as human cells and computational models, together with epidemiological and clinical studies. These tools will help facilitate human-relevant data acquisition, in an effort to face the increasing prevalence of Alzheimer’s disease.
A new commentary in the Journal of Alzheimer’s Disease by Physicians Committee medical research specialist Francesca Pistollato, Ph.D., and colleagues, addresses the need to refocus current research efforts on human-based methods, such as human cells and computational models, together with epidemiological and clinical studies. These tools will help facilitate human-relevant data acquisition, in an effort to face the increasing prevalence of Alzheimer’s disease.
Alzheimer’s disease research has been heavily focused on the use of animals in an effort to recapitulate human pathological features and test novel therapeutic compounds. However, research success has not effectively translated into therapeutic success for human patients.
References
- Pistollato F, Cavanaugh SE, Chandrasekera PC. A human-based integrated framework for Alzheimer’s disease research. J Alzheimers Dis. 2015;47:857-868.
